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Symptoms and causes of
Ledderhose disease

Ledderhose disease is commonly associated with pain and visible lumps in the feet. Although there is no singular cause, there are a number of factors that increase the likelihood you’ll develop the condition.

Ledderhose disease symptoms

Common symptoms of Ledderhose disease include:

Lumps growing and causing problems when trying to put on shoes
Pain or discomfort in your foot when walking or running
Tightening of the skin on the underside of the foot

If you have lumps in the underside or arch of your foot and are experiencing any of these symptoms, you should book an appointment with one of our consultants, who are leading experts in treating Ledderhose disease with radiotherapy.

Feet & legs of runner on tarmac

Who does Ledderhose disease affect?

Ledderhose disease usually occurs in middle-aged and older people, though it can develop in younger adults too. You may be more prone to the disease if you have:

  • Dupuytren’s contracture (around 50% of Ledderhose patients have Dupuytren’s contracture too)
  • A family history of either Ledderhose disease or Dupuytren’s contracture
Shoed feet of someone reclining on a balcony

Ledderhose disease causes

There’s no single cause for Ledderhose disease, but there are several risk factors that are associated with developing the condition:

  • Smoking
  • Diabetes
  • Liver disease
  • Medication for epilepsy
  • Injury or surgery to the foot